HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 LOADS BATCHED TUMOR-PROMOTING MICRORNAS INTO SMALL EXTRACELLULAR VESICLES WITH THE ASSIST OF CAVEOLIN-1 IN A549 CELLS

MicroRNAs in small extracellular vesicle (sEV-miRNAs) have been widely investigated as crucial regulated molecules secreted by tumor cells to communicate with surroundings.It is of great significance to explore the loading mechanism of sEV-miRNAs by tumor cells.Here, we comprehensively illustrated a reasoned loading pathway of batched tumor-promoti

This study revolves around the ballistic response of Al2O3/Al 5083-H116 bi-layer armour against 12.7 mm AP here tracer projectile.The study features the experimental and numerical study where the penetration of the AP projectile through a semi-infinite Al 5083-H116 target and Al2O3/Al 5083-H116 armour were determined.The semi-infinite Al 5083-H116

Abstract Background Benthic ciliates and the environmental factors shaping their distribution are far from being completely understood.Likewise, deep-sea systems are amongst the least understood ecosystems on Earth.In this study, using high-throughput DNA sequencing, we investigated the diversity and community composition of benthic ciliates in dif

The objective of this study was to evaluate accuracy, precision and robustness of two methods to obtain silage samples, in comparison with extraction of liquor by manual screw-press.Wet brewery residue alone or combined with soybean hulls and citrus pulp were ensiled in laboratory silos.Liquor was extracted by a manual screw-press and a 2-mL aliquo

Diffuse idiopathic pulmonary neuroendocrine cell (DIPNECH syndrome) remains unfamiliar to most clinicians even though it was first described almost 30 years ago.Diagnosis is usually confirmed histopathologically after lung biopsy, but often, a diagnosis or suspected diagnosis can be made radiographically.In this paper, we present a case report of a